Carcinoma adenoide cístico intraósseo: relato de caso

Abstract

Salivary gland tumors correspond to an average of 3 to 10% of all neoplasms that affect the buccomaxillofacial complex, with benign tumors being more frequent. However, malignant tumors can also affect patients, such as adenoid cystic carcinoma, and intraosseous involvement is uncommon. The present study aims to report a clinical case of a female patient, 36 years old, who presented a major complaint of swelling on the right side of the face. Extraoral examination revealed facial asymmetry and extensive swelling. On intraoral examination, lesions were observed extending to the premolar and molar region, extending in front of the midline, with erythematous and ulcerated areas. Radiographic examination revealed extensive bone destruction in the right maxilla, with extension to the buccal, nasal, maxillary sinus and orbital floor, as well as discontinuity of cortical and radiopaque fragments similar to bone trabeculation. Histopathological examination revealed basophilic cribiform islands invading trabecular bone, microcystic spaces, predominantly myoepithelial cells and rare true luminal cells. Upon immunohistochemical examination, the AE1 / AE3 and CK7 markers evidenced the epithelial cells, confirmed the epithelial and myoepithelial pattern of the lesion. The diagnosis was cystic adenoid carcinoma. The patient underwent surgical resection of the lesion and is under multiprofessional follow- up at the Oncology Service of Governador Valadares-MG for treatment.