Defeitos de desenvolvimento de esmalte não hereditários na dentição decídua como indicadores de eventos negativo de vida. Uma revisão sistemática

Abstract

The objective was to carry out a systematic review to determine the prevalence of enamel defects in the deciduous dentition and its association with negative events of early life. This research followed Prism Statement to report systematic revisions and meta-analysis. PubMed, Web of Science, Scopus, Science Direct, Ebscohost and Scientific Electronic Library (Scielo), Google Scholar were analyzed. It was used a previously defined standard search without restrictions on publication data or languages. Studies that evaluated the presence of enamel development defects and associated factors in children with deciduous dentition between 2 and 6 years of age were included, and studies were excluded when evaluated enamel defects due to fluorotic, hereditary or genetic causes; molar-incisors hypomineralization; as well as literature revisions; Patents; comments; publisher letters; Abstracts; Posters or similar presentations that were not primary studies. The selection of articles was made by two independent reviewers, using the same eligibility criteria, previously trained and calibrated. A third reviewer participated when there was disagreement in the selection. In the first stage, the duplicate records were excluded, and the evaluation of the study titles using the eligibility criteria. In the second stage, the summaries followed by the stage, of full reading of the full text. The bibliographic cross review of the references of the studies was carried out of the final sample and later the evaluation of the quality of the studies through the use of Newcastle-Ottawa Scale (NAS) and Strobe for observational studies. Sociodemographic, behavioral, related to disease, sex, sex, medical and dental history of the child, frequencies, n, confidence intervals, inference measures, and other results relevant to study were extracted, and other. These data were organized, categorized in spreadsheets and treated using the statistical program Stata 12. 3482 articles were identified and after the use of eligibility criteria remained 35 articles that underwent quality analysis were excluded 15 studies. The final sample analyzed was 20 studies that complied with the criteria. In the sample, the average prevalence of non -hereditary enamel defects of children between 6 and 60 months was 41.3%, being between 13.1%and 73.3%. Most of the defects (61.1%) were the opacities of these 45% were the demarcated type, and 66.7% were located in the incisors. Regarding association between enamel defects and early life events, 95% of studies found association between the presence of enamel defects and early negative life events, and 57.9% were associated with negative events during childbirth including delivery Premature and low birth weight, 42.1% negative events during the first years of life including malnutrition and lack of breastfeeding and 26.3% negative events during pregnancy including infections or diseases during pregnancy and low intrauterine weight of the baby. The prevalence of non -hereditary enamel defects in deciduous dentition is high and has been associated with early negative life events, especially during childbirth and the early years of the baby's life.