Associação dos sintomas do trato urinário inferior com a variabilidade da frequência cardíaca e componentes da aptidão física em homens normotensos

Abstract

Introduction: the symptoms of lower urinary tract symptoms have prevalence and harm the quality of life. They share an inadequacy of fitness as a risk factor for autonomic changes, metabolic syndromes and cardiovascular diseases. Associations like these enable preventive and therapeutic actions. We could not find, in the searching literature, which assessed the association of lower urinary tract symptoms with the heart rate variability and variables of fitness in normotensive men without chronicle disease report. Objective: to evaluate the association of lower urinary tract symptoms with heart rate variability and physical fitness in normotensive men. Methods: a case-control study was conducted with 89 men, 34 in the case group with lower urinary tract symptoms and 55 in the control group without lower urinary tract symptoms. The groups were compared in relation to physical activity level, anthropometric measures, flexibility, maximum oxygen consumption (VO2max) and heart rate variability. Results: patients with lower urinary tract symptoms presented lower physical activity levels (OR = 0.20, 95% CI = 0.08 to 0.49, p < 0.001), lower VO2max (OR = 0.07, 95% CI = 0.08 to 0.49, p < 0.001), and lower flexibility (OR = 0.31, 95% CI = 0.11 to 0.83, p = 0.015). Regarding heart rate variability, the very low frequency index did the case group present a statistically lower value (p = 0.032). However, in the multivariate analysis, only VO2max (OR = 0.12, 95% CI = 0.03 to 0.39, p = 0.001) and physical activity level (OR = 0.26, 95% CI = 0.19 to 0.70; p = 0.007) maintained a statistical association with lower urinary tract symptoms. Conclusions: Men with lower urinary tract symptoms present decreased values of the very low frequency spectral component of heart rate variability. Men with VO2max equal to or greater than 33 ml.kg.min-1 are 88% less likely to develop lower urinary tract symptoms and those with physical activity level equal to or greater than 150 minutes per week are 74% less likely to have lower urinary tract symptoms.