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Type: Artigo de Periódico
Title: Síntese e caracterização de complexos de platina(IV) com derivados N-benzilados da 1,3-propanodiamina
Other Titles: Synthesis and characterization of platinum(IV) complexes derived from N-benzyl-propanediamine
Author: Fontes, Ana Paula Soares
Almeida, Mauro Vieira de
Faria, Bruno de Araújo
César, Eloi Teixeira
Resumo: -
Abstract: The present work describes the synthesis of a series of platinum(IV) complexes with N-benzyl 1,3-propanediamine derivatives. Since substitution of the axial ligands in the platinum(IV) complexes may alter their pharmacological properties, we have prepared complexes with different groups, such as hydroxide, chloride and acetate using a sequence of substitution reactions. The resulting complexes were fully characterized by IR, 1H, 13C and 195Pt NMR spectroscopies, and elemental analysis.
Keywords: Platinum(IV) complexes
Anticancer agents
CNPq: -
Language: por
Country: Brasil
Publisher: -
Institution Initials: -
Access Type: Acesso Aberto
Issue Date: 2010
Appears in Collections:Artigos de Periódicos

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