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Type: Artigo de Periódico
Title: Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
Author: Vilela, Fernanda Maria Pinto
Fonseca, Yris Maria
Vicentini, Fabiana T. M. C.
Fonseca, Maria José Vieira
Amaral, Maria da Penha Henriques do
Resumo: -
Abstract: An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention.
Keywords: 3-benzophenone
Octylmethoxycinnamate
Octylsalicylate
CNPq: -
Language: eng
Country: Brasil
Publisher: -
Institution Initials: -
Access Type: Acesso Aberto
DOI: http://dx.doi.org/10.1590/S0100-40422011000500026
URI: https://repositorio.ufjf.br/jspui/handle/ufjf/8449
Issue Date: 2011
Appears in Collections:Artigos de Periódicos



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