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Type: Artigo de Periódico
Title: Desenvolvimento e validação de método analítico para determinação do teor de sinvastatina em cápsulas magistrais
Other Titles: Development and validation of analytical method for determination of simvastatin in capsules
Author: Polonini, Hudson Caetano
Santos, Felipe Cerqueira dos
Vaz, Urias Pardócimo
Brandão, Marcos Antônio Fernandes
Raposo, Nádia Rezende Barbosa
Ferreira, Anderson de Oliveira
Resumo: -
Abstract: Simvastatin is an oral anti-hyperlipidemic that has been widely used to reduce the cardiovascular disease risk. There isn't any pharmacopoeic method to assay this drug in capsules. It was proposed and validated a method for determining the content of simvastatin in capsules by UV/visible spectrophotometry (l = 237 nm), a more affordable method for the compounding pharmacy. The method was validated for linearity, specificity, range, accuracy, precision, performance, robustness, and limits of detection and quantification.
Keywords: Simvastatin
Validation studies
CNPq: -
Language: por
Country: Brasil
Publisher: -
Institution Initials: -
Access Type: Acesso Aberto
Issue Date: 2011
Appears in Collections:Artigos de Periódicos

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