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Chemical composition and antifungal activity of essential oil from Eucalyptus smithii .pdf2.63 MBAdobe PDFThumbnail
Type: Artigo de Periódico
Title: Chemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes
Author: Baptista, Edilene Bolutari
Franco, Danielle Cristina Zimmermann
Lataliza, Alexandre Augusto Barros
Raposo, Nádia Rezende Barbosa
Resumo: -
Abstract: INTRODUCTION: In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507. METHODS: Morphological changes in these fungi after treatment with the oil were determined by scanning electron microscopy (SEM). The antifungal activity of the oil was determined on the basis of minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values. RESULTS: The compound 1,8-cineole was found to be the predominant component (72.2%) of the essential oil. The MIC values of the oil ranged from 62.5μg•mL−1 to >1,000μg•mL−1, and the MFC values of the oil ranged from 125μg•mL−1 to >1,000μg•mL−1. SEM analysis showed physical damage and morphological alterations in the fungi exposed to this oil. CONCLUSIONS: We demonstrated the potential of Eucalyptus smithii essential oil as a natural therapeutic agent for the treatment of dermatophytosis.
Keywords: Eucalyptus smithii
Medicinal plants
Antifungal activity
Essential oil
CNPq: -
Language: eng
Country: Brasil
Publisher: -
Institution Initials: -
Access Type: Acesso Aberto
Issue Date: Nov-2015
Appears in Collections:Artigos de Periódicos

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