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Type: Artigo de Periódico
Title: Integrative literature review of the reported uses of serological tests in leprosy management
Author: Fabri, Angélica da Conceição Oliveira Coelho
Carvalho, Ana Paula Mendes
Vieira, Nayara Figueiredo
Bueno, Isabela de Caux
Rodrigues, Rayssa Nogueira
Monteiro, Thayenne Barrozo Mota
Oliveira, Rodrigo Correa
Duthie, Malcolm S.
Lana, Francisco Carlos Félix
Resumo: -
Abstract: An integrative literature review was conducted to synthesize available publications regarding the potential use of serological tests in leprosy programs. We searched the databases Literatura Latino-Americana e do Caribe em Ciências da Saúde, Índice Bibliográfico Espanhol em Ciências da Saúde, Acervo da Biblioteca da Organização Pan-Americana da Saúde, Medical Literature Analysis and Retrieval System Online, Hanseníase, National Library of Medicine, Scopus, Ovid, Cinahl, and Web of Science for articles investigating the use of serological tests for antibodies against phenolic glycolipid-I (PGL-I), ML0405, ML2331, leprosy IDRI diagnostic-1 (LID-1), and natural disaccharide octyl-leprosy IDRI diagnostic-1 (NDO-LID). From an initial pool of 3.514 articles, 40 full-length articles fulfilled our inclusion criteria. Based on these papers, we concluded that these antibodies can be used to assist in diagnosing leprosy, detecting neuritis, monitoring therapeutic efficacy, and monitoring household contacts or at-risk populations in leprosy-endemic areas. Thus, available data suggest that serological tests could contribute substantially to leprosy management.
Keywords: Serologic tests
Recombinant proteins
Mycobacterium leprae
CNPq: -
Language: eng
Country: Brasil
Publisher: -
Institution Initials: -
Access Type: Acesso Aberto
Issue Date: Mar-2016
Appears in Collections:Artigos de Periódicos

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