Evidências atuais no tratamento do ceratocisto odontogênico

Abstract

The odontogenic keratocyst is a cystic lesion with great potential for aggression and recurrence, for which there are several types of treatment described in the literature, such as enucleation, marsupialization, and decompression before enucleation, application of modified Carnoy's solution without chloroform, cryotherapy, use of 5-fluorouracil and resection. The most effective treatment to prevent recurrence is highly controversial in the literature, but many studies are debating the subject. The aim of this study was therefore to carry out a literature review highlighting the current evidence on the treatment of this lesion. To this end, a search was carried out in the PubMed and SciELO databases, including articles published between 2011 and 2023, using the following descriptors: "odontogenic keratocyst", "treatment", "marsupialization" and "peripheral osteotomy". From this study, we can conclude that it is essential for dentists to keep up to date with the literature on the various modalities and their effectiveness. Enucleation alone is not a good method of treatment in terms of lesion recurrence and is better indicated when accompanied by other modalities. As for the use of 5-fluorouracil, more research and randomized clinical studies are needed, and the choice of radical or partial resection has restricted indication due to the high degree of morbidity for the patient.