Efeito agudo da suplementação de arginina sobre a pressão arterial de repouso e pós-exercício aeróbico

Abstract

The arginine (ARG) is an amino acid indispensable in feeding and a natural precursor of nitric oxide (NO), which has vasodilatory action. The aerobic exercise cause physiological responses, among which, induces an increase in NO production through shear stress that occurs during exercise and remains increased after the exercise. In this sense, it can be assumed that the association between aerobic exercise and ARG supplementation may increase post-exercise hypotension (PEH). Thus, the aim of the present study was to evaluate the effects of acute ARG supplementation on HPE. Fourteen physically active young men participated in this randomized, double-blind, crossover clinical trial. All were submitted to two experimental sessions, one with previous ARG and one with placebo consumption, both with 30 minutes of moderate intensity aerobic exercise. Heart rate and systolic and diastolic blood pressures were measured before, at 30 and 60 minutes post-exercise. Data were tested by two-way ANOVA for repeated samples. Compared to pre-exercise values, systolic blood pressure decreased up to 60 min post-exercise (117.3±6.5 vs. 109.6±7.2 mmHg, P=0.001), mean blood pressure reduction (89.1±7.0 vs. 83.8±8.2 mmHg, P=0.024), heart rate (67.1±11.9 vs. 84.8±6.8 bpm, P=0.001) and double product (7988±1372 vs. 9734±990 mmHg.bpm, P=0.006) increased until 30 min post-exercise. Acute ARG supplementation did not significantly influence in cardiovascular responses. Results showed no effect of acute ARG supplementation on PEH in young men.