Perfil farmacoepidemiológico de município de médio porte da zona da mata mineira: estudo de utilização de medicamentos

Abstract

The production and dissemination of knowledge on quantitative standards of drug use, prescription profiles, quality of what you use, self-medication, sales and comparative costs contribute to the formation of a critical conscience of society in the use of drugs. The utilization studies of drug, as a arms of pharmacoepidemiology, has as a major objective is to generate information that can rationalize the use of drugs. The study evaluated the pharmacoepidemiological profile of the city of Muriaé, MG, through a study of utilization study of drug in community and hospital pharmacies. Was evaluated the use of manufactured and manipulated drugs by record sales in 4 pharmacies without manipulation and 3 with manipulation, for 3 months, furthermore collected 800 prescriptions for evaluating the quality of these same establishments. The prescriptions were assessed by the WHO prescribing indicators, the presence of essential information and legibility. In four hospitals in the city was evaluated the use of cardiovascular drugs, psychotropic and antibiotics for 3 months, and the results were expressed as defined daily dose (DDD) per 100 beddays. The study showed that was prescribed an average of 2.2 drugs per prescription common, what percentage of antibiotics prescribed was 22.1%, that 33% of prescriptions were for generic name and that 46.5% of prescription drugs contained in RENAME. The prescriptions were in 68% of cases little readable or unreadable and essential information were largely absent from the prescriptions. The drugs marketed in more than 30%, are not present in the RENAME, there was a high consumption of fixed-dose combinations and of antimicrobials, elevated use of drugs without therapeutic value high. Furthermore, most products marketed in manipulation pharmacies are different from without manipulation. In the hospital study cephalosporins (51.1%) were the most commonly used antimicrobials and use in DDD/100 was 45.69, considered the 10 most used antimicrobial agents. Among the cardiovascular antithrombotics (23.12%) and ACEI / ARB (22.80%) were the most commonly used groups. Anxiolytics (35%) were the most commonly used class of psychoactive drugs, especially the Midazolam (38.15 DDD/100) and Diazepam (29.10 DDD/100). These results show that the use of drugs in the city, which can be repeated in cities of similar size. As in Brazil there are still gaps in this information pharmacoepidemiological, this work may contribute to new studies and serve as a model for their implementation, and contribute to the formulation of health strategies in the field of drugs.