Associação de três protocolos do teste de sentar e levantar com o desempenho muscular dos membros inferiores em pacientes em hemodiálise

Abstract

Objective: Some evidence supports that the sit-to-stand (STS) tests can be used to evaluate muscle performance as they are quick and safe to perform, inexpensive, and have high testretest reliability in end-stage renal disease patients. Therefore, the aim of this study was to evaluate the association of three protocols of the STS test with muscle force output of the knee extension and flexion measured by handheld dynamometer in patients on hemodialysis and subjects without chronic kidney disease. Methods: This cross-sectional study included hemodialysis group [n = 60, 59.5 (16.8) years, 55% female] and control group [n = 60, 43.0 (11.8) years, 50% female]. The assessments were performed in two days, and the participants were submitted to three protocols of STS test (5-repetition STS, 10-repetition STS and 30s STS) or muscle force output of the knee extension and flexion evaluation by handheld dynamometer based on randomization. Patients included in the hemodialysis group were assessed before the start of the second or third hemodialysis session of the week. The subjects of the control group were evaluated at any time convenient to them. Results: The hemodialysis group presented reduced muscle force output of the extension (57.8 ± 2.2 vs. 91.7 ± 4.3 N.m) and knee flexion [19.8 (11.0) vs. 33.4 (20.4) N.m], longer time to perform the 5 STS (11.1 ± 0.4 vs. 8.5 ± 0.3s) and 10 STS tests [22.4 (9.1) vs. 17.3 (7.3)s], and lower number of repetitions in the 30s STS test [12.5 (4.0) vs. 17.0 (6.0)] when compared to the control group, respectively. The three STS tests were associated with muscle force output of the knee extension in the hemodialysis group, in which the 10-repetition STS test showed the best association. The multiple linear regression model showed that 10-repetition STS test time was significantly associated with the muscle force output of the knee extension, gender and body mass index (R2= 0.47; Adjusted R2= 0.42). Nevertheless, the only association between STS test and muscle force output of the knee extension in the control group was found in the 10-repetition STS test (R2= 0.20; Adjusted R2= 0.13). Conclusions: The three protocols of STS tests were associated with muscle force output of the knee extension in patients on hemodialysis. However, the 10-repetition STS test was the best protocol to estimate the quadriceps muscle torque in these patients.