Associação entre Lúpus Eritematoso Sistêmico e Doença Periodontal

Abstract

The understanding of clinical oral manifestations related to systemic conditions has been constant so that relationships between these conditions can be established. Systemic diseases can present oral clinical aspects directly associated with initial signs or disease activity that can mean diagnosis and consequent early treatment, improving the individual's prognosis. One of these systemic conditions is Systemic Lupus Erythematosus, a chronic inflammatory autoimmune disease that has inflammatory mechanisms and mediators that are very similar to Periodontal Disease. Thus, the aim of the study was to review the literature on the relationship between periodontal disease and Systemic Lupus Erythematosus. A possible positive relationship between these two diseases calls attention to the impact of inflammatory proteins in both situations. However, more work is needed on the topic to better elucidate the pathophysiological mechanisms of this interaction.