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dc.creatorReis, Roberta Cristina Novaes dos-
dc.creatorOda, Simone do Carmo-
dc.creatorAlmeida, Mauro Vieira de-
dc.creatorLourenço, Maria C. S.-
dc.creatorVicente, Felipe R. C.-
dc.creatorRaposo, Nádia Rezende Barbosa-
dc.creatorTrevizani, Rafael-
dc.creatorSantos, Priscila L. C.-
dc.creatorHyaric, Mireille Le-
dc.date.accessioned2019-02-13T14:29:24Z-
dc.date.available2019-02-13-
dc.date.available2019-02-13T14:29:24Z-
dc.date.issued2008-
dc.citation.volume19pt_BR
dc.citation.issue6pt_BR
dc.citation.spage1065pt_BR
dc.citation.epage1072pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/S0103-50532008000600003pt_BR
dc.identifier.urihttps://repositorio.ufjf.br/jspui/handle/ufjf/8948-
dc.description.abstractN-monoalkylated diamines were synthesised and treated with D-ribonolactone or D-gluconolactone. The resulting aldonamides were evaluated for their antimicrobial activity against S. aureus, E. coli, M. tuberculosis and C. albicans. Two hydrazides were also prepared from ribonohydrazide and their biological activity was compared to their amide analogues. All the ribono-derivatives displayed moderated antitubercular activity, and some of them were also active against S. aureus.pt_BR
dc.description.resumoDiaminas N-monoalquiladas foram sintetizadas e tratadas com D-ribonolactona ou D-gliconolactona. As aldonamidas resultantes foram avaliadas para atividade antimicrobiana contra S. aureus, E. coli, M. tuberculosis and C. albicans. Duas hidrazidas foram também preparadas a partir da ribonoidrazida e suas atividades biológicas comparadas com aquelas de análogos amida. Todos os derivados da ribonolactona mostraram ter atividade antitubercular moderada, alguns foram ativos também contra S. aureus.pt_BR
dc.languageengpt_BR
dc.publisher-pt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initials-pt_BR
dc.relation.ispartofJournal of the Brazilian Chemical Societypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAntimicrobialpt_BR
dc.subjectM. tuberculosispt_BR
dc.subjectAmphiphilicpt_BR
dc.subjectAldonamidept_BR
dc.subject.cnpq-pt_BR
dc.titleSynthesis and antimicrobial activity of amphiphilic carbohydrate derivativespt_BR
dc.typeArtigo de Periódicopt_BR
Appears in Collections:Artigos de Periódicos

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