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dc.creatorDias, Alyria Teixeira-
dc.creatorCastro, Sandra Bertelli Ribeiro de-
dc.creatorAlves, Caio César Souza-
dc.creatorRezende, Alice Belleigoli-
dc.creatorRodrigues, Michele Fernandes-
dc.creatorMachado, Rachel Rocha Pinheiro-
dc.creatorFernandes, Adriana-
dc.creatorCorrêa, Deborah Negrão-
dc.creatorTeixeira, Henrique Couto-
dc.creatorFerreira, Ana Paula-
dc.date.accessioned2019-01-15T14:12:56Z-
dc.date.available2019-01-11-
dc.date.available2019-01-15T14:12:56Z-
dc.date.issued2011-
dc.citation.volume106pt_BR
dc.citation.issue5pt_BR
dc.citation.spage617pt_BR
dc.citation.epage619pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/S0074-02762011000500015pt_BR
dc.identifier.urihttps://repositorio.ufjf.br/jspui/handle/ufjf/8460-
dc.description.abstractThe presence of intestinal helminths can down-regulate the immune response required to control mycobacterial infection. BALB/c mice infected with Mycobacterium bovis following an infection with the intestinal helminth Strongyloides venezuelensis showed reduced interleukin-17A production by lung cells and increased bacterial burden. Also, small granulomas and a high accumulation of cells expressing the inhibitory molecule CTLA-4 were observed in the lung. These data suggest that intestinal helminth infection could have a detrimental effect on the control of tuberculosis (TB) and render coinfected individuals more susceptible to the development of TB.pt_BR
dc.description.resumo-pt_BR
dc.languageengpt_BR
dc.publisher-pt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initials-pt_BR
dc.relation.ispartofMemórias do Instituto Oswaldo Cruzpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectM. bovis - Spt_BR
dc.subjectVenezuelensispt_BR
dc.subjectCoinfectionpt_BR
dc.subjectILpt_BR
dc.subject17pt_BR
dc.subjectCTLApt_BR
dc.subject4pt_BR
dc.subjectTuberculosispt_BR
dc.subject.cnpq-pt_BR
dc.titleLower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensispt_BR
dc.typeArtigo de Periódicopt_BR
Appears in Collections:Artigos de Periódicos



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