https://repositorio.ufjf.br/jspui/handle/ufjf/8460
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Lower production of IL-17A and increased susceptibility to Mycobacterium.pdf | 915.16 kB | Adobe PDF | View/Open |
DC Field | Value | Language |
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dc.creator | Dias, Alyria Teixeira | - |
dc.creator | Castro, Sandra Bertelli Ribeiro de | - |
dc.creator | Alves, Caio César Souza | - |
dc.creator | Rezende, Alice Belleigoli | - |
dc.creator | Rodrigues, Michele Fernandes | - |
dc.creator | Machado, Rachel Rocha Pinheiro | - |
dc.creator | Fernandes, Adriana | - |
dc.creator | Corrêa, Deborah Negrão | - |
dc.creator | Teixeira, Henrique Couto | - |
dc.creator | Ferreira, Ana Paula | - |
dc.date.accessioned | 2019-01-15T14:12:56Z | - |
dc.date.available | 2019-01-11 | - |
dc.date.available | 2019-01-15T14:12:56Z | - |
dc.date.issued | 2011 | - |
dc.citation.volume | 106 | pt_BR |
dc.citation.issue | 5 | pt_BR |
dc.citation.spage | 617 | pt_BR |
dc.citation.epage | 619 | pt_BR |
dc.identifier.doi | http://dx.doi.org/10.1590/S0074-02762011000500015 | pt_BR |
dc.identifier.uri | https://repositorio.ufjf.br/jspui/handle/ufjf/8460 | - |
dc.description.abstract | The presence of intestinal helminths can down-regulate the immune response required to control mycobacterial infection. BALB/c mice infected with Mycobacterium bovis following an infection with the intestinal helminth Strongyloides venezuelensis showed reduced interleukin-17A production by lung cells and increased bacterial burden. Also, small granulomas and a high accumulation of cells expressing the inhibitory molecule CTLA-4 were observed in the lung. These data suggest that intestinal helminth infection could have a detrimental effect on the control of tuberculosis (TB) and render coinfected individuals more susceptible to the development of TB. | pt_BR |
dc.description.resumo | - | pt_BR |
dc.language | eng | pt_BR |
dc.publisher | - | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.initials | - | pt_BR |
dc.relation.ispartof | Memórias do Instituto Oswaldo Cruz | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | M. bovis - S | pt_BR |
dc.subject | Venezuelensis | pt_BR |
dc.subject | Coinfection | pt_BR |
dc.subject | IL | pt_BR |
dc.subject | 17 | pt_BR |
dc.subject | CTLA | pt_BR |
dc.subject | 4 | pt_BR |
dc.subject | Tuberculosis | pt_BR |
dc.subject.cnpq | - | pt_BR |
dc.title | Lower production of IL-17A and increased susceptibility to Mycobacterium bovis in mice coinfected with Strongyloides venezuelensis | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
Appears in Collections: | Artigos de Periódicos |
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