Simulação da perfusão cardíaca por contraste no miocárdio utilizando uma formulação de escoamento em meios porosos

Abstract

We present a simplifed computational model that characterizes the spatio-temporal dynamics of blood perfusion in cardiac myocardium. Specifically, we are interested in reproducing qualitative images obtained by contrast-enhanced exams, which are widely used in clinical medicine to evaluate the blood perfusion in the heart. The aplication of contrast allows the detection of injuries, ischemic regions, fibrosis or tumors. Here we focus on the pathological case associated to subendocardial infarct. In our modelling, we will consider the tissue of cardiac myocardium as a porous media, i.e., a solid region with empty spaces. To this end, the modelling was based on differential equations and Darcy's Law, which correlates tissue permeability, pressure difference and the blood ow in the cardiac tissue.