Modelagem eletromecânica do coração com autômato celular e sistemas massa-mola

Abstract

This work proposes a computational heart model named FisioPacer, which aims to reproduce the electrical pulse propagation over the cardiac tissue and its mechanical deformation. In order to perform fast simulations, it was used a cellular automaton coupled with a mass-spring system. A genetic algorithm was also used to automatically adjust model parameters, in order to reproduce in silico experiments and a real left ventricle behavior. For the model validation, seventy two experiments were performed and the results were compared to another robust simulator, based on partial differential equations. The comparisons showed that the FisioPacer simulator could reproduce cardiac tissue electromechanics, with up to 15000-fold improvement in computational time. Furthermore, a real patient left ventricle was simulated, with data obtained via MRI.